effects of depression on myocardial perfusion scintigraphy [persian]

introduction: the relationship between depression and coronary artery disease is well established; however assessment of this relationship using functional and semi-quantitative imaging (myocardial perfusion scintigraphy) was lacking. the aim of this study was to assess the relationship between the severity of depression and the severity of myocardial perfusion abnormality. methods: patients were assessed with rest/stress 99mtc-mibi myocardial perfusion scintigraphy using single photon emission computed tomography (spect) and beck depression inventory (bdi-ii). visual and semi-quantitative assessment of myocardial perfusion score (mps) in a five-scale measurement for standard 20-segment-model were used. results: when all patients (n=167) were evaluated, no correlation was found between mps and bdi-score. considering only those with significant perfusion abnormality (mps95) (p=0.097), but other myocardial walls failed to show such association. conclusion: in patients with significant perfusion abnormality, the greater is this abnormality the more severe is the depression. also patients with inferior wall infarction, have a higher bdi-score as compared with normal subjects.